Diabetes mellitus is a condition characterized by the failure of the body to take up the sugar (glucose) from the bloodstream to generate energy. Glucose is a vital source of energy for the cells that form muscles and tissues. It is also the major source of energy for the brain tissue.
When glucose enters your bloodstream, it requires assistance—a "key"—to reach its intended destination. Insulin, a hormone, acts as that key. Diabetes develops when your pancreas does not produce enough or any insulin, or when your body does not adequately respond to insulin's effects. Diabetes affects individuals of all ages.
The primary cause of diabetes depends greatly on its type. However, regardless of the type of diabetes, it might result in high blood sugar levels. Too much sugar in the bloodstream can cause major health complications.
Type 1 and type 2 diabetes are both chronic diseases. Prediabetes and gestational diabetes are two potentially reversible diabetes disorders. Prediabetes occurs when blood sugar levels are above normal. However, the blood sugar levels are not high enough to be considered diabetic. Furthermore, prediabetes might progress to diabetes if no preventative measures are implemented. Gestational diabetes occurs during pregnancy. However, it may resolve once the baby is delivered.
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Following are the early signs that appear at the onset of diabetes:
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The risk factors for diabetes vary according to its type. These risk factors include family history and environmental factors. Sometimes family members of type 1 diabetes patients should be tested for the presence of autoantibodies (diabetes immune system cells). If you have these autoantibodies in your blood, you have a high risk of developing type 1 diabetes. Also, it is not compulsory that anyone who has these autoantibodies will develop diabetes.
Race and ethnicity may also increase your risk of acquiring type 2 diabetes. Certain populations, notably Black, Hispanic, American Indian, and Asian Americans, are at a greater risk. Overweight and obese persons are more likely to develop prediabetes, type 2 diabetes, and gestational diabetes.
Following are the main causes of diabetes in adults:
| Cause Category | Explanation | Related Diabetes Type(s) (Full Forms Included) |
| Insulin Resistance | Cells in muscles, fat, and liver do not respond properly to insulin. Factors include obesity, sedentary lifestyle, poor diet, hormonal imbalance, genetics, and certain medications. | Type 2 Diabetes (T2D) |
| Autoimmune Attack | The immune system destroys insulin-producing beta cells in the pancreas. | Type 1 Diabetes (T1D), LADA – Latent Autoimmune Diabetes in Adults |
| Hormonal Imbalances | Pregnancy hormones cause insulin resistance → gestational diabetes. Other hormonal disorders like Cushing syndrome and acromegaly also impair insulin regulation. | GDM – Gestational Diabetes Mellitus, Type 2 Diabetes (T2D) |
| Pancreatic Damage | Pancreatitis, pancreatic surgery, or injury reduces insulin production. | Type 3c Diabetes (Pancreatogenic Diabetes) |
| Genetic Mutations | Mutations in specific genes affect insulin production/function. | MODY – Maturity Onset Diabetes of the Young; Neonatal Diabetes Mellitus (NDM) |
| Long-term Medication Use | Drugs such as corticosteroids and HIV/AIDS medications increase insulin resistance or reduce insulin secretion. | Type 2 Diabetes (T2D) – Secondary Diabetes |
Following are five main aspects of diabetes management in adults:
Being diagnosed with diabetes is tragic, but it does not deprive you from living a happy and healthy lifestyle. Diabetes management requires continual attention and dedication. While it may be daunting at first, you will eventually gain a better understanding of how to manage the illness and be in sync with your own body.
Get expert guidance from top diabetologists in Mumbai at Surya Hospitals. Book your consultation now!
Q1: What is the difference between type 1 and type 2 diabetes?
A: Type 1 is autoimmune and insulin-dependent, while Type 2 usually develops from insulin resistance and lifestyle factors.
Q2: Can diabetes occur without symptoms?
A: Yes, many adults with type 2 diabetes have no noticeable symptoms in the early stages.
Q3: Is diabetes reversible?
A: Some people with early type 2 diabetes can achieve remission with significant lifestyle changes and weight loss, but it must be medically supervised.