Bone Marrow Failure Syndromes: Treatment & Care

Bone Marrow Failure Syndromes

We at Surya vastly specialise in treating blood illnesses such as bone marrow failure syndromes. Bone marrow failure syndromes are uncommon, and their frequency varies with subtype. Aplastic anaemia, for example, is estimated to have an annual incidence of 2 to 5 cases per million population, but MDS has a higher prevalence, particularly in elderly people.

Failure is not an option, especially when it comes to your health. Excel in your wellness journey with the finest care for Bone Marrow Failure Syndrome.

Types of Bone Marrow Failure Syndromes

There are several forms of bone marrow failure syndromes, each with its own set of causes and symptoms. Some examples of frequent types are:

Aplastic Anaemia: It occurs when the bone marrow does not create enough red blood cells, white blood cells, or platelets.
Fanconi Anaemia: It is an inherited condition that affects numerous organs, including the bone marrow, resulting in anaemia i.e. a reduction in blood cell production.
Diamond-Blackfan Anaemia: This rare genetic illness predominantly impairs the synthesis of red blood cells, resulting in severe anaemia.
Shwachman-Diamond Syndrome: This syndrome affects several organs, including the bone marrow, resulting in diminished blood cell production.

What are the causes of Bone Marrow Failure Syndromes?

Bone marrow failure syndromes can be caused by a variety of factors, including:

Some bone marrow failure diseases are caused by inherited genetic mutations. Fanconi anaemia and Diamond-Blackfan anaemia are caused by inherited genetic abnormalities that disrupt blood cell formation and function.
Aplastic anaemia, myelodysplastic syndromes (MDS), and paroxysmal nocturnal hemoglobinuria (PNH) are examples of acquired diseases that can lead to bone marrow failure.
Certain chemicals, radiation, or poisons may have a role in the development of bone marrow failure disorders.

How do we diagnose you?

At Surya Hospitals, we use a thorough and sophisticated diagnostic approach, that includes:

Complete Blood Count (CBC)
Peripheral Blood Smear
Bone Marrow Aspiration and Biopsy
Platelet Function Tests
Blood Smear Examination for Clotting Disorders
Antiplatelet Antibody Tests
Hormone Level Tests
Genetic Testing
Ultrasound or Imaging Studies
Platelet Turnover Tests

Treatment

We provide a complete range of therapeutic options for the management of bone marrow failure syndromes at Surya Hospital's Bone Marrow Transplant facility. The most prevalent treatment methods include:

Blood Transfusions: To treat symptoms and enhance blood counts, transfusions of red blood cells, platelets, or other blood products may be delivered.
Medicines: Certain drugs may be prescribed to increase or decrease blood cell formation depending on the underlying aetiology of the condition of the immune system.
Stem Cell or Bone Marrow Transplant: A transplant may be considered for severe bone marrow failure diseases. To restore normal blood cell production, the defective bone marrow is replaced with healthy stem cells or bone marrow cells.
We provide ongoing supportive care, such as infection treatment, regular blood tests, and close monitoring of blood counts, to promote optimal health and well-being.

Frequently Asked Questions

What common symptoms are associated with syndromes of Bone Marrow Failure?

Weakness, exhaustion, bruising easily, recurrent infections, pale skin, and unexplained bleeding are possible symptoms. A healthcare professional's consultation is essential for a proper assessment.

Is it possible for BMFS to cause further health issues?

Anemia, infections, and bleeding disorders are among the consequences that can arise from untreated BMFS. It's essential to receive a diagnosis and treatment on time to stop more health problems.

Is it possible to control Bone Marrow Failure Syndromes with a change in lifestyle?

The main course of treatment for BMFS frequently includes medication interventions, even though lifestyle modifications may assist in managing symptoms. Seeking advice from a healthcare professional is necessary for customized treatment.

Does Bone Marrow Failure Syndromes impact pregnancy?

Those with BMFS may experience additional difficulties during pregnancy. The health of the individual and the fetus depends on close observation and close coordination with medical professionals.

Is there a certain age range in which Bone Marrow Failure Syndromes are more prevalent?

A person of any age, including adults and children, can be impacted by BMFS. Different age groups may experience BMFS in different ways and with different prevalence rates.