Paediatric Kidney Transplant

Conditions that necessitate Kidney Transplants in children?

Our Pediatric Kidney Transplant program is prepared to treat a wide range of illnesses that may necessitate a Kidney Transplant in children. Some of the most prevalent conditions we treat are:

• Congenital Anomalies: We evaluate and treat patients born with kidney and urinary tract anomalies, including polycystic kidney disease, posterior urethral valves, and renal dysplasia that can lead to ESRD and the need for a kidney transplant.
• Glomerular Disorders: We offer specialist care to children with glomerular disorders such as nephrotic syndrome, IgA nephropathy, and membranous nephropathy who advance to ESRD and require kidney transplantation.
• We treat genetic kidney illnesses such as Alport syndrome, autosomal recessive polycystic kidney disease, and cystinosis, which may necessitate a kidney transplant as the disease advances.
• Renal Hypoplasia or Dysplasia: We examine and treat children with renal hypoplasia or dysplasia, which are disorders in which the kidneys do not fully mature or are physically incorrect, resulting in ESRD and the need for a kidney transplant.
• Acquired ESRD: We provide kidney transplantation for children who develop ESRD due to an acquired cause. Chronic glomerulonephritis, systemic lupus erythematosus, and kidney damage caused by drugs or infections are examples of such disorders.

When should you consider seeing our experts?

Children with the following conditions may benefit from Kidney Transplantation:

• End-Stage Renal Disease (ESRD): Children with ESRD may require a Kidney Transplant to restore normal Kidney function since their Kidneys have lost their ability to operate properly.
• Dialysis Requirement: Children who require long-term dialysis to preserve their health due to Kidney failure may be the candidates for a Kidney Transplant as a more effective and long-term therapeutic option.
• Children with ESRD who have a major reduction in their quality of life, such as growth failure, malnutrition, and dialysis problems, may benefit from a kidney transplant to improve their overall well-being.
• Candidates for Kidney Transplantation should be evaluated to ensure they have no contraindications such as active infections, uncontrolled malignancies, or significant cardiovascular or pulmonary disease that may impair their ability to undergo surgery and recover successfully.

How children are diagnosed?

A combination of pre-transplant evaluations, compatibility assessments, and post-transplant monitoring are used in the diagnostic testing for children's kidney transplants. The following are the main diagnostic procedures used in juvenile kidney transplantation:

• Blood Typing and Crossmatching
• Tissue Typing (HLA Typing)
• Crossmatch Test
• Antibody Screening
• Blood and Urine Tests
• During and After Transplant
• Renal Arteriogram
• Ultrasound Imaging
• Renal Biopsy
• Doppler Ultrasound
• Immunosuppressive Drug Monitoring
• Cystoscopy
• Urodynamic Studies
• CT Scan or MRI
• Regular Blood and Urine Tests

How to prepare for a Pediatric Kidney Transplant?

A thorough and interdisciplinary preparation is necessary for pediatric kidney transplant surgery. To guarantee compatibility and the best possible results, both the child and the possible kidney donor—whether alive or deceased—go through assessments. Key actions to do in order to get ready for a juvenile kidney transplant include:

• Recipient Assessment
• Donor Assessment
• Compatibility testing and blood typing
• Immunological Evaluation
• Counselling before surgery

What follows after the Transplant?

• Immediately following surgery, the child is under strict observation at the hospital's transplant facility. The state of the kidneys, vital signs, and general health are closely monitored.
• The duration of hospitalization varies but usually extends to multiple days in order to track any indications of problems or rejection.
• Immunosuppressive drugs will be given to the child in order to stop the transplanted kidney from being rejected by the immune system.
• Depending on how well the child is recovering, a gradual return to regular activities is advised, including physical education classes and school attendance. A recommendation for physical therapy to support rehabilitation may be made.
• It is crucial to regularly check for potential side effects like as infections, high blood pressure, and post-transplant diabetes. The transplant staff takes care of any problems right away.
• Follow-up consultations are held less frequently as the child's recuperation advances.
• The family and the child may receive advice on particular lifestyle changes, such as recommended exercise regimens and food choices.